Welcome to the Dr. Ling Cai Lab!
Research Interests
Bioinformatics, data integration
Cancer metabolism
Inborn errors of metabolism
Lung neoplasm
The Lung Cancer Autochthonous Model Gene Expression Database Enables Cross-Study Comparisons of the Transcriptomic Landscapes Across Mouse Models
Ling Cai, Fangjiang Wu, Qinbo Zhou, Ying Gao, Bo Yao, Ralph J. DeBerardinis, George K. Acquaah-Mensah, Vassilis Aidinis, Jennifer E. Beane, Shyam Biswal, Ting Chen, Carla P. Concepcion-Crisol, Barbara M. Grüner, Deshui Jia, Robert A. Jones, Jonathan M. Kurie, Min Gyu Lee, Per Lindahl, Yonathan Lissanu, Corina Lorz, David MacPherson, Rosanna Martinelli, Pawel K. Mazur, Sarah A. Mazzilli, Shinji Mii, Herwig P. Moll, Roger A. Moorehead, Edward E. Morrisey, Sheng Rong Ng, Matthew G. Oser, Arun R. Pandiri, Charles A. Powell, Giorgio Ramadori, Mirentxu Santos, Eric L. Snyder, Rocio Sotillo, Kang-Yi Su, Tetsuro Taki, Kekoa Taparra, Phuoc T. Tran, Yifeng Xia, J. Edward van Veen, Monte M. Winslow, Guanghua Xiao, Charles M. Rudin, Trudy G. Oliver, Yang Xie, John D. Minna
Cancer Res 15 May 2025; 85 (10): 1769–1783. https://doi.org/10.1158/0008-5472.CAN-24-1607
High Glucose Contribution to the TCA Cycle Is a Feature of Aggressive Non–Small Cell Lung Cancer in Patients
Ling Cai, Nia G. Hammond, Alpaslan Tasdogan, Massar Alsamraae, Chendong Yang, Robert B. Cameron, Peiran Quan, Ashley Solmonson, Wen Gu, Panayotis Pachnis, Mayher Kaur, Brianna K. Chang, Qin Zhou, Christopher T. Hensley, Quyen N. Do, Luiza Martins Nascentes Melo, Jessalyn M. Ubellacker, Akash Kaushik, Maia G. Clare, Isabel N. Alcazar, Katarzyna Kurylowicz, Joseph D. Marcuccilli, Gabriele Allies, Andrea Kutritz, Joachim Klode, Vijayashree Ramesh, Thomas J. Rogers, Aparna D. Rao, Hannah E. Crentsil, Hong Li, Fang Brister, Phyllis McDaniel, Xiaohong Xu, Bret M. Evers, Lauren G. Zacharias, Jessica Sudderth, Jian Xu, Thomas P. Mathews, Dwight Oliver, John D. Minna, John Waters, Sean J. Morrison, Kemp H. Kernstine, Brandon Faubert, Ralph J. DeBerardinis
Cancer Discov 1 April 2025; 15 (4): 702–716. https://doi.org/10.1158/2159-8290.CD-23-1319
Lipoylation inhibition enhances radiation control of lung cancer by suppressing homologous recombination DNA damage repair
Jui-Chung Chiang, Zengfu Shang, Tracy Rosales, Ling Cai, Wei-Min Chen, Feng Cai, Hieu Vu, John D Minna, Min Ni, Anthony J Davis, Robert D Timmerman, Ralph J DeBerardinis, Yuanyuan Zhang
Sci. Adv. 11, eadt1241(2025). DOI:10. 1126/sciadv. adt1241