Welcome to Quantitative Biomedical Research Center

Meet some of the talented faculty members, staff, and students in the Quantitative Biomedical Research Center (QBRC) at UT Southwestern Medical Center.

Members

In the QBRC, we have multiple research labs for interdisciplinary biological research. Collaboration and teamwork are our keywords here.

Research Labs

We provide online tools and packages for biological research. Our computational biology team is continually releasing software to aid with statistical analysis.

Softwares

We welcome talented students, postdoctoral researchers, and faculty members to join us. We also greatly welcome any questions or comments regarding the QBRC.

Contact Us



Yang Xie, M.D., Ph.D.

Director of Quantitative Biomedical Research Center, Associate Professor, Clinical Center, UT Southwestern Medical Center

Study links deficiency of cellular housekeeping gene with aggressive forms of breast cancer


Based on an analysis of two large databases on breast cancer, reduced activity of an autophagy gene, beclin 1, was related to both a higher incidence of triple-negative breast cancer and a poorer prognosis for breast cancer patients.


The study, published in the online journal EBioMedicine, is the first to document a correlation between beclin 1 and triple-negative human breast cancer and validates research in mouse models.


“Patients with breast cancer and low beclin 1 expression had a 67 percent increase in the risk of dying from breast cancer compared with patients who had higher levels of beclin 1 expression,” Dr. Xie said.