User Groups

The Pediatric Cancer Data Core supports and receives input from various user groups across a range of disciplines and regions.

experimental therapeutics and precision medicine

The proposed PCDC will support all the components in the CMCD/UTSW ET/PM programs.

Examples of major use cases in ET and PM programs.

Investigator ET/PT Programs Cohort Discovery Data and Sample Access & Analysis
Clinical Sample Image Genomic
Kless Susceptibility Yes Yes Yes Yes
Brugarolas Immuno, Xenografts Yes Yes Yes Yes
Tomlinson Susceptibility Yes Yes
Laetsch Clinical Trials Yes Yes Yes
DeBerardinis Metabolism Yes Yes Yes
Skapek Sequencing, Xenografts Yes Yes Yes Yes
Koh Microbiomics Yes Yes Yes
Li Immuno Yes Yes Yes
Amatruda Sequencing Yes Yes Yes Yes Yes
Mendell Discovery Yes Yes Yes
Zhu Discovery Yes Yes Yes Yes

Contributors/Users


Laura Klesse, M.D., Ph.D.
Department of Pediatrics, UTSW
Kathleen Lugwig, M.D.
Department of Pediatrics, UTSW
James Brugarolas, M.D., Ph.D.
Department of Internal Medicine
Director of the Kidney Cancer Program, UTSW
Gail E Tomlinson, M.D., Ph.D.
Children’s Cancer Research Institute
UT Health Science Center at San Antonio
Ralph J. DeBerardinis, M.D., Ph.D.
Children's Medical Center Research Institute, UTSW
Stephen X. Skapek, M.D.
Chief of the Division of Hematology‐Oncology
Prof. Dept. of Pediatrics, UTSW
Joshua Mendell, M.D., Ph.D.
Department of Molecular Biology, UTSW

Andrew Y. Koh, M.D.
Departments of Pediatrics and Microbiology,
UTSW and CMCD
Hao Zhu, M.D.
Children's Medical Center Research Institute, UTSW

James Amatruda, M.D., Ph.D.
Children’s Hospital Los Angeles,
Keck School of Medicine of the University of Southern California
Bo Li, Ph.D.
Departments of Bioinformatics and Immunology, UTSW

population research and cancer survivorship research

Big data and technology are starting to change the methods of population research in prevention, epidemiology, and improving quality of care in cancer survivors.

Contributors/Users


Simon J. Craddock Lee, Ph.D., M.P.H.
Department of Clinical Sciences, UTSW
Philip J. Lupo, Ph.D.
Department of Pediatrics,
Baylor College of Medicine / Texas Children’s Hospital
Alice A. Holland, Ph.D., A.B.P.P.
Department of Psychiatry, UTSW
Madhukar H. Trivedi, M.D.
Department of Psychiatry, UTSW

computational research

Tools for data collection and data storage
                                                                    

Examples of computational research.

PI Institution Research Area
Junzhou Huang UT Arlington CS, Image analysis
Ovidiu Daescu UT Dallas CS, Machine learning
Jim Ji Texas A&M EE, Image analysis
Daehwan Kim UTSW CS, Genomic analysis
Marina Vannucci Rice Stat, Data integration

Contributors/Users


Junzhou Huang, Ph.D.
Department of Computer Science and Engineering,
UT Arlington
Ovidiu Daescu, Ph.D.
Associate Department Head of Computer Science,
UT Dallas
Jim Ji, Ph.D.
Department of Electrical and Computer Engineering,
Texas A & M University
Daehwan Kim, Ph.D.
Department of Boinformatics,
UTSW
Marina Vannucci, Ph.D.
Noah Harding Professor and Chair of Statistics,
Department of Statistics,
Rice University